2 of 19

Green Bay Packers at San Francisco 49ers (FOX)

GB
Robert Hanashiro-USA TODAY

The San Francisco 49ers open against the Green Bay Packers for the second straight year this time at Candlestick. The Packers have been waiting for payback all offseason, but Colin Kaepernick and the Niners are too much to handle for the Pack.

San Francisco 49ers defeat Green Bay Packers 35-28 to go 1-0.

3 of 19

San Francisco 49ers at Seattle Seahawks (NBC)

SEA
Steven Bisig-USA TODAY Sports

Coming off a tough battle against the Packers, San Francisco must now travel to the hardest place to play in the NFL for Seattle's home opener against their biggest rival. The Seahawks were undefeated at home last year and continue their winning streak.

Seattle Seahawks defeat San Francisco 49ers (1-1) 24-23.

4 of 19

Indianapolis Colts at San Francisco 49ers (CBS)

Colts
Thomas J. Russo-USA TODAY Sports

The Niners continue there tough start to the schedule taking on their third straight playoff team in Andrew Luck and the Indianapolis Colts. They put up a fight in a shootout, but their too young and defense can't handle Kaepernick and the Niners.

San Francisco (2-1) defeats Indianapolis Colts 32-24.

5 of 19

San Francisco 49ers at St. Louis Rams

STL
Jeff Curry-USA TODAY Sports

The 49ers have struggled with the Rams as of late and you won't believe this, but they tie (AGAIN!) 24-24 in what continues to be a bizarre in-division battle.

San Francisco 49ers (2-1-1) tie St. Louis Rams. 24-24.

6 of 19

Houston Texans at San Francisco 49ers (NBC)

HOU
Troy Taormina-USA TODAY Sports

The 49ers get their third primetime game in their first five games and it comes against AFC South champion Houston Texans. The 49ers notoriously play well in primetime and escape their five game gauntlet with a win and a (3-1-1) record.

San Francisco 49ers (3-1-1) defeat Houston Texans 28-23.

7 of 19

Arizona Cardinals at San Francisco 49ers

AZ
Cary Edmondson-USA TODAY Sports

Carson Palmer returns to the Bay Area to take on the 49ers. Arizona is improved, but their offensive line allows Palmer to get crushed over and over.

San Francisco 49ers (4-1-1) defeat Arizona Cardinals 38-13.

8 of 19

San Francisco 49ers at Tennessee Titans

Titans
Cary Edmondson-USA TODAY Sports

San Francisco starts their long road trip by visiting Tennessee and taking on former TE Delanie Walker and the Titans. The Niners capitalize on Jake Locker mistakes and slow down Chris Johnson to continue their win streak.

San Francisco 49ers (5-1-1) defeat Tennessee Titans 41-16.

9 of 19

San Francisco 49ers at Jacksonville Jaguars (London)

Jags
Cary Edmondson-USA TODAY Sports

The 49ers go across the pond to take on the lowly Jaguars. San Francisco won their only game in London when they defeated the Denver Broncos. Jaguars are in rebuild mode and the long trip doesn't hurt the Niners as much as people may think.

San Francisco 49ers (6-1-1) defeat Jacksonville Jaguars 28-3.

10 of 19

Bye Week

Bye
Brian Spurlock-USA TODAY Sports

The 49ers end their cross-country and exhaustive trip from Tennessee to London with a record of 6-1-1, which is a great feat after playing four playoff teams from a year ago. A much needed week off will help rest the veteran 49ers before returning to Candlestick to take on the Carolina Panthers.

11 of 19

Carolina Panthers at San Francisco 49ers

CAR
Bob Donnan-USA TODAY Sports

The Panthers take on three of the four Conference Champion teams in 2013 and this one is a battle of the dual-threat QBs. Colin Kaepernick will make the Panthers regret taking Cam Newton over him in the draft.

San Francisco 49ers (7-1-1) defeat Carolina Panthers 27-20.

12 of 19

San Francisco 49ers at New Orleans Saints

NOLA
Derick E. Hingle-USA TODAY Sports

San Francisco returns to the scene of their heartbreaking Super Bowl loss when they travel to New Orleans. Sean Payton faces the Niners for the first time since the Divisional Playoff loss and the Bounty Scandal and they get some retribution in a shootout.

New Orleans Saints defeat San Francisco 49ers (7-2-1) 35-31.

13 of 19

San Francisco 49ers at Washington Redskins

Wash
Geoff Burke-USA TODAY Sports

San Francisco visits RGIII and the Redskins in a battle of two of the most exciting players in the NFL. The 49ers struggle with the read option and lose their second straight game for the first time all season.

Washington Redskins defeat San Francisco 49ers (7-3-1) 27-24.

14 of 19

St. Louis Rams at San Francisco 49ers

STL
Jeff Curry-USA TODAY Sports

The 49ers finally break through and beat the Rams with the Rams missing a running game and receivers on the outside, the Niners defense clamps down and defeats their in-division rival.

San Francisco (8-3-1) 49ers defeat St. Louis Rams 31-21.

15 of 19

Seattle Seahawks at San Francisco 49ers

SEA
Steven Bisig-USA TODAY Sports

This game will determine the winner of the NFC West and who will ultimately host a playoff game in the NFC. San Francisco has their own home advantage and wins a defensive battle on a goal-line stand.

San Francisco 49ers (9-3-1) defeat Seattle Seahawks 17-13.

16 of 19

San Francisco 49ers at Tampa Bay Buccaneers

TB
Jason O. Watson-USA TODAY Sports

The 49ers travel cross-country to Florida to take on the Bucs and former safety Dashon Goldson in what could be a trap game after a bloodbath against the Seahawks the previous week. The 49ers overcome and dominate Josh Freeman and Tampa Bay.

San Francisco 49ers (10-3-1) defeat Tampa Bay Buccaneers 34-18.

17 of 19

Atlanta Falcons at San Francisco 49ers

ATL
John David Mercer-USA TODAY Sports

The rematch of the NFC Championship game, Tony Gonzalez returns to beat the Niners and the Falcons upgraded their shoddy running game after signing Steven Jackson. The Niners are at home this time and win on a late field goal that will help them in playoff seeding.

San Francisco 49ers (11-3-1) defeat Atlanta Falcons 38-35.

18 of 19

San Francisco 49ers at Arizona Cardinals

AZ
Kyle Terada-USA TODAY Sports

San Francisco ends the regular season by traveling to Arizona in a game they must win to hold onto the division against the Seahawks. Arizona plays them strong in another game where the Niners could be looking ahead, but their defense forces some turnovers and the Niners win handily.

San Francisco 49ers (12-3-1) defeat Arizona Cardinals 31-10.

19 of 19

12-3-1, NFC West Champions

Crab
Robert Hanashiro-USA TODAY

The San Francisco 49ers end the regular season (12-3-1) and win the NFC West by 1/2 game over the Seattle Seahawks. A huge feat since no one wants to travel to Seattle for a playoff game.


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