2 of 11

10. Trent Richardson

Richardson
Pat Lovell - USA TODAY Sports

Richardson’s calf injury has him listed as questionable for the Indianapolis Colts’ matchup against the Arizona Cardinals this weekend, but that’s not the only way this injury will be costly for the Colts. The Colts traded a first-round pick to the Cleveland Browns to bolster a running game, which has been lacking for years in Indianapolis. Thus far, Richardson has failed to live up to even conservative expectations. He’s losing carries to Donald Brown, so even if his lack of production doesn’t cost the team wins, the failure of the trade is becoming more evident every week.

3 of 11

9. Jay Cutler

Cutler
Mike Dinovo - USA TODAY Sports

Cutler seems to be progressing well in his recovery from an ankle injury, and backup Josh McCown has performed well in his absence. The Bears are playing a sneaky-good St. Louis Rams squad this weekend, and Chicago’s locked in a battle with Detroit for NFC North supremacy. It’s possible Cutler won’t be needed this weekend, but if McCown struggles or the Bears start to trail early, they won’t have anywhere else to turn at the signal caller position.

4 of 11

8. Adrian Peterson

Peterson
Bruce Kluckhohn - USA TODAY Sports

Adrian Peterson struggled last week with both the Seattle Seahawks’ vaunted defense, as well as a sore groin. He insists it won’t keep him out this week against the Green Bay Packers, but since “All Day” is the only good thing happening for the Minnesota Vikings lately, anything that slows him down is bad news for the Norsemen.

5 of 11

7. Calvin Johnson

Megatron
Mike Dinovo - USA TODAY Sports

Still dealing with a knee injury, Megatron is unlikely to miss time. However, he’s going up against Darrelle Revis, who held Johnson to just one catch for 13 yards in their last matchup in 2010, and Revis is still one of the best corners in the league, despite playing for the struggling Tampa Bay Buccaneers. Johnson is the driving force of the Lions’ offense, and they’ll need him at full strength.

6 of 11

6. Mike Pouncey

Pouncey
Kim Klement - USA TODAY Sports

As bad as things have gotten for the Miami Dolphins in the public relations department, it’s easy to forget that, at 5-5, they still have a shot at a playoff spot in the AFC. While the offensive line lost both Richie Incognito and Jonathan Martin in the locker room scandal, they’ll also likely be without center Mike Pouncey for a second straight week. They face the streaking Carolina Panthers on Sunday, and must find a way to keep Ryan Tannehill standing and open holes for Lamar Miller if they have any chance at victory.

7 of 11

5. Wes Welker

Welker
Kyle Terada - USA TODAY Sports

If you could guess just one date that Wes Welker would have circled on his calendar, you’d have to say it would be this Sunday. After a messy split from the New England Patriots, Welker joined former rival Peyton Manning in Denver, and must have been champing at the bit for this weekend’s prime-time return to Foxboro.

Dealing with the effects of a concussion suffered last weekend, Welker is still questionable to even play in this game, and despite the Patriots’ struggles on defense, Manning can’t be looking forward to meeting Tom Brady with less than his full complement of offensive weapons.

UPDATE: Welker has been cleared to play against New England by league medical staff, and should be ready to go on Sunday night. Still, any setbacks would cost the Broncos dearly.

8 of 11

4. J.J. Watt

Watt
Troy Taormina - USA TODAY Sports

Watt missed some practice time earlier this week with a sore back, but the heart and soul of the Houston Texans’ defense says he’ll be ready to go against the Jacksonville Jaguars this weekend. The Texans have been in a freefall over the last several weeks. Despite the Jaguars’ poor performance this year, the Texans can’t afford to lose any production on defense.

9 of 11

3. Aqib Talib

Talib
Jeremy Brevard - USA TODAY Sports

Ice up, son. Steve Smith’s short and sweet advice to the New England Patriots’ cornerback has gone viral, and Talib is still dealing with the hip injury that cost him some time in that game against the Carolina Panthers. Along with Talib, cornerbacks Alfonzo Dennard and Kyle Arrington have also been limited in practice. With Peyton Manning and the Broncos next up on the schedule, secondary issues are the last thing the Patriots need right now.

10 of 11

2. Aaron Rodgers

Rodgers
Pat Lovell - USA TODAY Sports

Having missed several games already, Rodgers’s availability this week was never in question, but the reality that the Green Bay Packers and their fans have had to come to terms with is that this team goes as Rodgers goes. Scott Tolzien, the starter against the Minnesota Vikings this weekend, has completed nearly 66 percent of his passes this year, but has thrown just one touchdown to five interceptions. The Packers are only one game back in the NFC North, but a loss this weekend could severely dampen any remaining playoff hopes in Green Bay.

11 of 11

1. Sean Lee

Lee
Jeffrey Pittenger - USA TODAY Sports

Lee, who has been one of the Dallas Cowboys’ best players on defense this season, is going to miss the NFC East showdown with the rival New York Giants. There are rumblings that he could be able to return from a hamstring injury as early as Thanksgiving, but more likely he’ll be out at least until a Week 14 game at Chicago. Lee has been excellent in 2013, with 93 tackles and four interceptions so far, and the Cowboys will need every bit of help they can get in that stacked division.


Related NFL Injuries

Benny Cunningham St. Louis Rams
Concussions Have Status of 3 St. Louis Rams Starters in Doubt for Week 13
Pat Lovell-USA TODAY Sports
Indianapolis Colts: Enough With Injury Excuses
Timothy T. Ludwig - USA Today Sports
Can Kansas City Chiefs Fight Off San Diego Chargers?
Mark L. Baer-USA TODAY Sports
Injuries In Secondary Could Spell Doom For New England Patriots vs. Denver Broncos

Related Slideshow

Jamaal Charles
Predicting What Final 2014 NFL Playoffs Brackett Will Look Like
Pittsburgh Steelers-Ben Roethlisberger5
Ranking Every NFL Team’s Schedule Strength for Rest of 2013 Regular Season
C.J. Spiller Cover
5 Players Who Need To Step Up For Buffalo Bills During Stretch Run
Raven Defense
5 Baltimore Ravens Players That Need To Step Up In Week 13 vs. Pittsburgh Steelers

Around the Web

ZergNet

From Our Partners