Fantasy Football Start'em, Sit'em: Week 1

The first week of fantasy football is here. That means matchups, injuries and uncertainty. Not to worry — we’ve got you covered.

QB – Start Andrew Luck if you have him. Don’t be hesitant on the Indianapolis Colts‘ star passer anymore because he’s going to go wild against the Oakland Raiders‘ porous defense. On the flips side, don’t start Cam Newton. Sure, he’s considered an elite fantasy QB, but the Seattle Seahawks‘ defense is going to make life tough for the Carolina Panthers‘ signal-caller on Sunday.

RB – Definitely put David Wilson in your starting lineup because he’s playing against a banged-up Dallas Cowboys defensive line that looks sure to allow plenty of running lanes on Sunday night. On a negative note, don’t bother putting Eddie Lacy in your starting lineup this week because he won’t find much running room against the San Francisco 49ers‘ tough front seven.

WR – T.Y. Hilton is going to beat the Raiders’ pathetic secondary deep at least twice on Sunday, so start him with confidence this week. A receiver who will greatly disappoint fantasy owners this week is Mike Wallace, who is going to be blanketed by Cleveland Browns star cornerback Joe Haden.

TE – Put Zach Sudfeld in your starting lineup this week because he could see a ton of targets as the only healthy, halfway-reliable tight end on the field for the New England Patriots against the Buffalo Bills. Make sure Jermichael Finley is on your bench because the 49ers allowed fewer fantasy points to opposing tight ends than any other team in 2012.

D/ST – Start the Colts’ defense against the Raiders. Terrelle Pryor is going to turn the ball over at least three times, which means lots of fantasy points for Indy. Do not start the Baltimore Ravens‘ defense against the Denver Broncos. That’s just stupid.